Why Axie Aid?

Axie Aid was developed and tested right here at Fantaxies, where our medication is made in carefully controlled small batches. We’re so confident in this medication that we use it on our own personal pet lotls, as well as those in our breeding colony. There are many products on the market geared to treat diseases for fish but hardly any for axolotls. Many of these fish medications contain ingredients that are not suitable for use on axolotls due to their sensitive and permeable skin. Yet axolotls need love too! And when illness comes up, proper treatment can prove life-saving. Home remedies often are not powerful enough to combat more moderate to serious issues, and other treatments can expose you to carcinogenic chemicals or annihilate your live plants.

  • Broad-spectrum to target a large range of diseases

  • Safe for axolotls, most aquarium plants and fish

  • Gentle, yet effective

  • Degrades naturally, safe for the environment

  • No water changes required to remove

  • Changes color when inactive

Buy Axie Aid

Axie Aid Directions:

  • Bypass filtration & remove invertebrates before use. Maintain good aeration during treatment with an airstone. Do not perform water changes before or during treatment. Treat in the morning. For every 20 gallons, use 3 Tablespoons of treatment daily for 4 days. The water will turn bright pink, then amber when treatment is no longer active. In soft water, reduce dosage by half.
  • Water should hold pink color for at least 6 hours. Repeat dose if pink color turns amber within 45 minutes. Repeat with half dose if pink color disappears after 1-2 hours.
  • When the water turns fully amber, resume filtration until the next treatment. A final treatment may be performed 3 days after the 4th treatment if necessary. After the last treatment, a water change may be done to remove amber color.
  • Normal behavior during treatment may include occasional scratching, clamped gills and darting. If the axolotl shows signs of extreme discomfort, such as rolling over or listing sideways, stop the active treatment immediately by performing a 75% water change or neutralizing with hydrogen peroxide. If the axolotl shows a peeling slime coat during or after treatment, perform a large water change and reduce the treatment strength for future treatments by half. At regular strength, it will not cause gill filament damage.
  • In case of severe illness or if the axolotl shows no improvement after the full treatment period, treatment (or retreatment) can be carried out at up to a double dose. This is especially useful in the case parasitic infection.

Quick Treatment Dosage Calculator

Tank Size Dosage
55 gallons 8 ¼ Tablespoons
50 gallons 7 ½ Tablespoons
40 gallons 6 Tablespoons
30 gallons 4 ½ Tablespoons
20 gallons 3 Tablespoons
10 gallons 1 ½ Tablespoons
5 gallons 2 ¼ teaspoons
2.5 gallons 1 teaspoon
1 gallon 40 drops


Active ingredients: Reagent-grade Potassium Permanganate

Inactive ingredients: Distilled water

Potassium permanganate is a purple crystal-like substance that is a powerful oxidizer. It naturally degrades into a harmless, eco-friendly substance.

Yes, Axie Aid is safe for almost all species of live plants. Hyacinths are an exception. It’s not a bad idea to remove prized/expensive specimens into a separate bucket of water during treatment (basically bypass the plants like you do the filter) just to be extra safe. That said, you may notice a big boost in plant growth in the following weeks after treatment as it provides an essential nutrient to the plants, so we recommend leaving the live plants in if you can.

Yes, Axie Aid is safe for almost all species of aquarium fish. It can be used to treat illnesses in fish as well. Great for quarantining feeders!

8 oz bottle treats up to 100 gallons of water.

16 oz bottle treats up to 200 gallons of water.

Bypassing the filter allows the medication to work in your tank without hurting the good bacteria in your filter. Doing this is easy. For hang on back filters and most other external filters, simply disconnect the power source to ensure no water is flowing through. (You’ll want to keep the media wet, though, to keep the bacteria alive). For internal filters such as sponge filters, remove them to a bucket of (untreated) tank water during treatment.

To neutralize with hydrogen peroxide, add 1/2 TB per 25 gallons of 3% hydrogen peroxide to deactivate. Allow 4 days before treating again as hydrogen peroxide can deactivate further treatments for that timeframe. Another method is to perform a large 75% water change. As with the peroxide method, dechlorinators used during the water change can deactivate further treatments.

To remove brown stains from using Axie Aid that has spilled on on fabric, upholstery, carpet or furniture, make a paste of cream of tarter and 3% hydrogen peroxide (the consistency of pancake batter) and gently rub the stain. Stains will be lifted from most materials using this simple method.

On the other hand, if it is the axolotl’s slime coat that has been stained brown, this will go away naturally as the cells slough off. It is an indication the treatment was too strong and should be reduced next time.